Plain-spoken, well-cited guides to the peptides and small molecules people in our community actually use. Half-lives, typical protocols, common stacks, side effects, and what the data actually says. Reviewed quarterly by a licensed clinician. Not medical advice.
Mounjaro · Zepbound · LY3298176
Dual GLP-1 / GIP agonist. FDA-approved. The current weight-loss benchmark.
Ozempic · Wegovy · Rybelsus
The original GLP-1. Mature data, well-characterized side effects, predictable dosing.
LY3437943 · Triple-G
Triple GLP-1 / GIP / GCG agonist in Phase III. ~24% weight loss at 48 weeks.
Ibutamoren · Nutrobal
The oral GH secretagogue — deepest human trial data in its category, heaviest side-effect profile.
NNC 26-0161
The cleanest GH secretagogue — a GH pulse without cortisol, prolactin, or appetite spike.
Mod GRF (1-29) · Modified GHRH
30-min half-life GHRH analogue. Most common stack partner for ipamorelin.
DAC-CJC · Drug Affinity Complex
Albumin-bound version with a ~8-day half-life. Sustained GH elevation — different side-effect calculus.
GHRH(1-29) · GRF(1-29) · Geref
The original natural-rhythm GH approach — your pituitary stays in charge.
Egrifta · TH9507
FDA-approved GHRH analogue for HIV-associated lipodystrophy. Visceral-fat targeted.
HEX · Examorelin
Potent GHRP — strongest GH pulse of its class, but with cortisol and prolactin elevation.
Pralmorelin · KP-102
Older-generation GHRP. Strong GH pulse with some cortisol/prolactin spike.
Histrelin analogue
Strong GHRP with significant appetite stimulation — the class hunger driver.
PEGylated Mechano Growth Factor
Pegylated IGF-1 splice variant. Targets satellite cells at sites of mechanical loading.
Long R3 IGF-1
Long-acting IGF-1 analogue — half-life ~20-30 hours. The systemic anabolic.
DES(1-3) IGF-1
Truncated IGF-1 analogue. Local, site-specific hypertrophy.
Mecasermin · Increlex
Recombinant human IGF-1. FDA-approved for severe primary IGF-1 deficiency.
Body Protection Compound 157 · PLD-116
Synthetic pentadecapeptide. Strong animal data, almost no human data — and the most-Googled healing peptide of the decade.
Thymosin Beta-4 · Tβ4
The systemic healing peptide — built for muscle tears and full-body inflammation.
Copper peptide · Lamin
Copper tripeptide for collagen synthesis, skin repair, and cosmetic recovery.
α-MSH (11-13) · Lys-Pro-Val
Anti-inflammatory tripeptide fragment of α-MSH. Mast-cell stabilizer for gut and skin.
Cathelicidin · hCAP-18
Endogenous antimicrobial peptide. Investigated for chronic infection, biofilm, and skin.
Tα1 · Zadaxin
28-aa immunomodulatory peptide. Approved in 30+ countries for hepatitis B/C and immune support.
Elamipretide · Bendavia
Mitochondrial-targeted peptide. Restores cristae integrity. Phase III for primary mitochondrial myopathy.
Mitochondrial Open Reading Frame of 12S rRNA-c
Mitochondrial-derived peptide. AMPK activator. Investigated for metabolic and exercise capacity.
Rattin · MDP
Mitochondrial-derived peptide. Cyto-protective. Investigated for Alzheimer and metabolic disease.
Vasoactive Intestinal Peptide
28-aa neuropeptide. Anti-inflammatory, immunomodulatory. Used for CIRS and Sjogren investigationally.
Bremelanotide · Vyleesi
Melanocortin receptor agonist. FDA-approved for HSDD. The non-vascular libido peptide.
MT-II · MT2
α-MSH analogue. Tanning, libido, appetite suppression — and a significant melanoma risk profile.
Afamelanotide · Scenesse · MT-I
α-MSH analogue. EMA/FDA-approved (Scenesse) for erythropoietic protoporphyria.
NS2330
Triple monoamine reuptake inhibitor. ~10% weight loss in Phase II. Late-stage development.
Steroidal SARM
Steroidal SARM and myostatin modulator. Hepatotoxic — not a peptide; a synthetic steroid.
NNMT inhibitor
Small-molecule NNMT inhibitor. Strong preclinical metabolic data, no human trials.
GH fragment (177-191)
GH fragment marketed for fat-loss. Mixed clinical data — most trials negative.
FST-344
Myostatin inhibitor. Powerful muscle-growth signal in animal models. Significant safety concerns.
ActRIIB-Fc · Ramatercept
ActRIIB-Fc decoy receptor. Development discontinued due to side effects in trials.
Epithalon · AEDG
Tetrapeptide investigated for telomerase activation. Russian-language source base. Thin evidence.
KP-10 · Metastin (45-54)
Upstream HPG-axis trigger. Studied for hypothalamic infertility and as a GnRH alternative.
cocoa flavanol
Flavanol from cocoa. Modest myostatin inhibition. Best evidence: vascular function.
5-Hydroxytryptophan
Direct serotonin precursor. Used for mood, sleep, and appetite. NEVER combine with SSRIs.
L-Carnitine L-tartrate · ALCAR
Fatty-acid shuttle. Modest endurance and recovery benefits. Cognitive variant (ALCAR) for brain.
Human Chorionic Gonadotropin · Pregnyl
LH analogue. Mimics LH to maintain testicular function on TRT or restart after a cycle.
Human Menopausal Gonadotropin · Menopur
Mixed LH/FSH gonadotropin. Used for full HPG restart and fertility.
Clomiphene Citrate · Serophene
The original SERM PCT. Two isomers — one helpful, one notorious for emotional side effects.
Trans-clomiphene · Androxal
The clean half of Clomid. Pure trans-isomer — endogenous testosterone without side effects.
Tamoxifen Citrate
SERM. Gold standard for gynecomastia prevention and PCT — gentler than Clomid emotionally.
Evista · Keoxifene
SERM. Stronger anti-estrogen action in breast tissue. The gyno-reversal compound.
Anastrozole
Aromatase inhibitor. The stronger, surgical AI for high-dose AAS cycles.
Exemestane
Suicide AI — permanently inactivates aromatase. No estrogen rebound on discontinuation.
Femara
The most potent AI. Crushes estrogen — useful for emergency gyno, dangerous for general use.
Caber · Dostinex
Dopamine D2 agonist. Crushes prolactin from 19-nor compounds and GH peptides.
Cypionate · Enanthate · Propionate · Sustanon
The base of nearly every cycle. Endogenous androgen, exogenous ester — TRT to supraphysiologic, on one molecule.
Tren · Finaplix · Parabolan
19-nor steroid. Most potent on the market — and the most punishing on sleep, cardiovascular, and mental health.
Oxandrolone · Var
The mild oral. DHT-derived, low side-effect profile — the most expensive and most counterfeited steroid on earth.
D-bol · Methandrostenolone
The original mass-builder. Fast water and strength — and the original liver-toxicity warning.
Stanozolol · Winny
The track-and-field cut-cycle classic. Hardening and strength without water, at a cost to joints and lipids.
Deca-Durabolin · Deca · NPP
19-nor anabolic. Joint relief and slow, steady mass — and the highest prolactin profile in the class.
Drostanolone · Mast
DHT-derived hardener. Anti-estrogenic. The classic stage-prep finisher with low side-effect noise.
Oxymetholone · A-bombs · A50
17α-alkylated oral. Fastest mass and strength of any compound. Hardest on the liver and lipids.
Equipoise · EQ · Bold
Long-ester veterinary anabolic. Slow, lean gains and notable appetite increase.
MK-2866 · Enobosarm
The most-studied SARM. Mildest profile — bridging tool for recomp and injury recovery.
Testolone
High-potency SARM, near testosterone-level anabolic signal. Hepatotoxicity reports in users.
Ligandrol · VK-5211
Potent SARM — clean, strength-focused. Strongest HPG suppression of the SARMs.
GW-501516 · GW
PPAR-δ agonist. Endurance and fat oxidation — also flagged for tumor formation in rodents.
S23
Strongest SARM in binding affinity. Investigated as a male contraceptive — full HPG shutdown.
S-4 · GTx-007
Older SARM with vision side effects (yellow tint). Recomp and lean dryness profile.
LGD3303
Less-known LGD analogue. Stronger anabolic ratio than LGD-4033 in rodents, minimal human data.
Glucophage · Fortamet
The most-studied small molecule on earth. AMPK activator. Off-label longevity use is now mainstream.
Sirolimus
mTOR inhibitor. The most-cited longevity drug. Weekly off-label dosing is the standard human protocol.
Nicotinamide Mononucleotide
NAD+ precursor. The Sinclair supplement. Strong cellular data, modest clinical effect sizes.
Nicotinamide Riboside · Niagen
NAD+ precursor. Better bioavailability than NMN. The pharma-backed competitor.
Pitocin · Syntocinon
The bonding hormone. Used investigationally for social anxiety, autism, and PTSD.
ACTH(4-10) Pro-Gly-Pro · Semax NA
Russian intranasal nootropic. ACTH(4-10) fragment. BDNF up-regulator. Best-studied in stroke.
Cerebrolysate · FPF-1070
Porcine-brain-derived neurotrophic peptide cocktail. Approved in 50+ countries for stroke and dementia.
TP-7 · Tuftsin analogue
Russian intranasal anxiolytic. Non-benzodiazepine. GABA-modulating without sedation or tolerance.
Delta Sleep-Inducing Peptide
9-aa neuropeptide. Investigated for chronic pain, alcohol/opioid withdrawal, and sleep architecture.
PNB-0408
Hepatocyte growth factor mimic. Oral, BBB-permeable. Investigated for Alzheimer disease.
CNTF (148-163) · P021
CNTF fragment peptide. Investigated for neurogenesis and memory in Alzheimer models.
Glu-Asp-Arg · EDR
Pineal tripeptide. Khavinson bioregulator — sparse human data, used for neuroprotection.
Reviewed quarterly · next audit Aug 20, 2026
Get notified when we update the library →Side-by-side guides on the 8 most-Googled comparison questions in the compound world.
Ozempic / Wegovy against Mounjaro / Zepbound — what SURMOUNT-5 actually showed.
→ HealingThe two most-stacked healing peptides. When to pick which, and the "Wolverine" stack.
→ Growth hormoneOral convenience vs injectable cleanliness. Same hormone, very different side-effects.
→ SARMsThe three most-used SARMs ranked. Anabolic effect vs HPG suppression.
→ PCTThe two SERMs that built PCT. Mood, vision, and the isomer problem.
→ LongevityTwo NAD+ precursors, two academic schools. What the human data actually shows.
→ AASTwo DHT-derived "cutting" orals. How they differ on joints, lipids, hardening.
→ GHRHThe three GHRH analogues. Half-lives, FDA status, and which to pick.
→Most peptide content on the internet treats every number as fact. We don't. Every claim on every page carries one of these four labels — so you know whether a half-life is from a Phase-III trial or a Reddit thread before you act on it.
Replicated trials with n > 100, mature peer-reviewed evidence, FDA precedent.
Small or single trials, animal-to-human extrapolation, early Phase 2 data.
User reports, dated forum threads, community surveys — cited and verifiable, not invented.
No data exists. We say so plainly rather than fill space.
Epti is the first training app built around your peptide protocol — workouts, dosing, side effects, and bloodwork that actually talk to each other.