Soft-tissue, mitochondrial, and immune peptides for recovery — from BPC-157 to SS-31.
Healing peptides fall into three categories. Soft-tissue repair (BPC-157, TB-500, GHK-Cu) targets localized injuries — tendons, ligaments, skin. Mitochondrial peptides (SS-31, MOTS-c, Humanin) target cellular energy and metabolic resilience. Immune modulators (KPV, LL-37, Thymosin α-1, VIP) target chronic inflammation, infection, and autoimmunity.
Most healing protocols combine 1–2 compounds. The most popular stack — BPC-157 + TB-500 — covers both local (angiogenesis, fibroblast migration) and systemic (actin regulation, anti-inflammation) pathways.
Body Protection Compound 157 · PLD-116 · PL-10 · PL14736
Synthetic pentadecapeptide. Strong animal data, almost no human data — and the most-Googled healing peptide of the decade.
Thymosin Beta-4 · Tβ4
The systemic healing peptide — built for muscle tears and full-body inflammation, where BPC-157 cannot reach.
Copper peptide · Lamin · Glycyl-L-histidyl-L-lysine copper
Copper tripeptide for collagen synthesis, skin repair, and cosmetic recovery.
Tα1 · Zadaxin
28-aa immunomodulatory peptide. Approved in 30+ countries for hepatitis B/C and immune support.
Cathelicidin · hCAP-18
Endogenous antimicrobial peptide. Investigated for chronic infection, biofilm, and skin.
Mitochondrial Open Reading Frame of 12S rRNA-c
Mitochondrial-derived peptide. AMPK activator. Investigated for metabolic and exercise capacity.
Elamipretide · Bendavia · MTP-131
Mitochondrial-targeted peptide. Restores cristae integrity. Phase III for primary mitochondrial myopathy.
Vasoactive Intestinal Peptide
28-aa neuropeptide. Anti-inflammatory, immunomodulatory. Used for CIRS and Sjogren investigationally.
α-MSH (11-13) · Lys-Pro-Val
Anti-inflammatory tripeptide fragment of α-MSH. Mast-cell stabilizer for gut and skin.
Rattin · MDP · MOTS-c sibling
Mitochondrial-derived peptide. Cyto-protective. Investigated for Alzheimer and metabolic disease.
| BPC-157 | TB-500 | GHK-Cu | KPV | |
|---|---|---|---|---|
| Best for | Tendons, gut | Muscle tears, systemic | Skin, collagen | Gut/skin inflammation |
| Route | SC, oral | SC | Topical, SC | SC, oral, topical |
| Half-life | Short | Long (days) | Short | Short |
| WADA | Banned | Banned | Permitted | Permitted |
BPC-157 is local — angiogenesis and growth-factor signaling at the injection site. TB-500 is systemic — actin regulation and cell migration body-wide. They are commonly stacked because the mechanisms are complementary, not competing.
BPC-157 has shown protective effects against NSAID-induced gut damage in animal models. Otherwise, most healing peptides have no documented interactions with NSAIDs.
Most users report inflammation and pain reduction within 5-14 days for soft-tissue compounds. Structural tissue remodeling (tendons, ligaments) takes 6-12 weeks and requires progressive mechanical loading.
Epti is the first training app built around your peptide protocol — workouts, dosing, side-effects, and bloodwork on one timeline.